Additional Procedures for Using Recombinant or Synthetic Nucleic Acid Molecules
The use of recombinant or synthetic nucleic acid molecules is regulated by federal guidelines and state statute. The use of recombinant or synthetic nucleic acid molecules requires registration and approval of the IBC. This includes all research involving the joining of natural or synthetic nucleic acid molecule segments to other nucleic acid molecules, as well as all synthetic or natural nucleic acid molecule segments that are being used for gene transfer into an in vivo system. All research must be conducted in accordance with the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines). Protocols involving gene therapy require review by the Recombinant DNA Advisory Committee (RAC) and review and approval by the University of Minnesota Institutional Review Board (IRB), in addition to IBC review and approval.